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Botulinum Toxin - 1 Vial x 150 IU
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| |  | | Package: 1 Vial x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | Price: $145.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is category-A toxin which encloses 150 IU in one vial and can be used into one patient. Botulinum Toxin Type A is a type of medication to correct light folds and shrink the face.
This product is a sterilized, lyophilized formula of cleansed botulinum toxin type A, manufactured from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium containing trypticase as well yeast extract. A series of purifying technique were taken to form a crystal clear complex consisting of the active high molecular weight toxin protein also an linked hemagglutinin. Next re-diluted and dialyzed the transparent toxin, a precise amount of the germ-free clarified (0.2 microns) toxin were added to a solution having gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
SUGGESTIONS:
This medication is indicated for the handling of blepharospasm, hemi facial spasm in grown-ups and some kinds of strabismus, particularly for acute paralytic strabismus, comitant strabismus, strabismus produced by endocrine myopathy and strabismus which cannot be adjusted through operation. Anti-Wrinkle, Thin faces and legs.
USAGE AND DOSING:
1. Location for insertion:
- For blepharospasm: the inoculation should be injected intramuscularly at some locations of upper and inferior covers, i.e., taking 4 to 5 points of insertion into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial spasm: besides the points mentioned above, three other locations on middle, lower face and cheek have to be inserted intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) may be injected at the locations of two parts of eyebrow, upper lip or the lower jaw according to the illnesses.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is injected using a coaxial electrode needle with electromyography direction or amplifier under topical anesthesia of 0.5% Decarine. The inoculations into additional ocular muscles are selected according to the type and place of strabismus.
2. Dose:
150 IU must be diluting into 2.0-2.5ml sterilized water before usage.
Thin with sterile normal saline agreeing to diverse requirements before using. The white loose product changes to be neutral or yellowish translucent solution after the diluting.
- For blepharopasm and hemi facial tremor: the injection can be suggested following above guidelines. The first dosage of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. In case the primary handling is considered deficient 1 week later, a supplementary injection can be indicated. Double dosing of 5 U / 0.1 ml could be indicated to recrudescent patients. But the limitation of total dose of 55 U for 1 inoculation and 200 U for 1 month should not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the first dosage into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the primary measure into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the initial measure into each muscle is 2.5 U and could be rised (to 5.0 each time) depending on the reaction; for persistent VI cranial nerve paralysis continued for more than one month. The inoculating volume into ever muscle should not ever 0.1 ml. To individuals, having insufficient reaction, supplementary insertion can be given. To recrudescent patients, the measure may be repeated or improved irregularly. But for each muscle the extreme dosing should be less than 5 U / inj.
The Thinning of BTXA:
The watering of BTXA with sterile normal saline has to be done sensibly on the basis of real desires. Succeding is a reference table of watering to be suggested. The vial should be trembling smoothly once adding sterile normal saline to the complete thinning. The thinning BTXA must be injected at once or maintained in freezer at 2-8 degrees as well to be administrated within 4 hours. The ampule also the needle used with BTXA as well as the remaining BTXA solution must be disposed after sterilization.
ADVERSE FEEDBACKS:
Passing ptosis of the eyelid, problem of the lesser eyelid, minimized blinking, eyelid close partly, weakness of facial muscles, etc. can arise to a number of patients who take this preparation treatment for blepharospasm as well hemi facial tremor. But, all the signs will go without any treatment within 3 to 8 weeks. Short-term also dissimilar degree of ptosis of the eyelid, vertical deviation as well rarely mydriasis, which allied to the circulation of the toxin to the muscles adjacent, can appear to some patients who take this injection treatment for strabismus. The symptoms will go without any remedy within a few weeks.
CONTRAINDICATIONS:
This medication is not indicated in people with anaphylactic structure and recognized allergy to this medication.
ADMONITIONS:
The injection process must be suggested later to people who have fever, acute infectious illness and carefully to the patients with heart, liver, lung problems, active tuberculosis, blood diseases also pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of medicines should not be taken during the inserting of BTXA (Botulinum Toxin Type A for Therapy).
BTXA (Botulinum Toxin Type A for Therapy) is in minim reaction or without any action to the persons in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus provoked by extremely grave surgery, chronic paralysis strabismus, and chronic VI or III cranial nerve paralysis, bad muscle fiber contracture.
1:1000 adrenalines have to be prepared in case of occasional accident.
SHELF LIFE:
Three years from the date of lyophilization. The result is obvious and may be last six months.
STORAGE:
Keep at a temperature of -5 to -20 gr C (23 to -4 gr F). Store unopened vial at -5 temperatures.
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