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Botulinum Toxin - 5 Vials x 150 IU
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| |  | | Package: 5 Vials x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | Price: $470.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is kind-A toxin which has 150 IU in one vial and can be injected into one patient. Botulinum Toxin Type A is a category of product to correct small wrinkles as well as shrink the face.
This medication is a hygienic, lyophilized formula of refined botulinum toxin type A, produced from the crude toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium containing trypticase also yeast extract. A sequence of purifying process were taken to make a galssy complex consisting of the active high molecular weight toxin protein and an related hemagglutinin. Next re-diluted and dialyzed the limpid toxin, an accurate volume of the germ-free clean (0.2 microns) toxin were added to a solution containing gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
SUGGESTIONS:
This preparation is suggested for the dealing of blepharospasm, hemi facial contraction in grown-ups also some kinds of strabismus, especially for acute paralytic strabismus, comitant strabismus, strabismus instigated by endocrine myopathy also strabismus which cannot be improved with operation. Anti-Wrinkle, Thin looks also legs.
USAGE AND DOSING:
1. Position for injection:
- For blepharospasm: the injection should be used intramuscularly at some locations of superior also inferior lids, i.e., taking 4 to 5 places of insertion into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other points on middle, lower face and cheek should be inserted intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) can be injected at the places of two sides of eyebrow, upper lip or the lower jaw agreeing to the illnesses.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is injected using a coaxial electrode syringe with electromyography supervision or amplifier under topical anesthesia of 0.5% Decarine. The inoculations into extra ocular muscles are selected according to the type and position of strabismus.
2. Dosage:
150 IU must be diluting into 2.0-2.5ml sterilized water before inoculating.
Melt with sterile normal saline according to diverse requests before administrating. The white loose product changes to be neutral or yellowish transparent solution after the .
- For blepharopasm and hemi facial spasm: the insertion may be given following above advices. The initial dose of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the primary cure is considered deficient 1 week later, an additional inoculation could be suggested. Dual dosing of 5 U / 0.1 ml may be suggested to recrudescent persons. But the restriction of total dosing of 55 U for one inoculation and 200 U for 1 month should not be overdone.
- For strabismus: for vertical and horizontal muscle strabismus of less than 20 prism diopters, the initial dosing into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dosing into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the initial measure into every muscle is 2.5 U and could be increase (to 5.0 each time) depending on the reply; for persistent VI cranial nerve paralysis lasted for more than one month. The injecting volume into each muscle should not ever 0.1 ml. To patients, having insufficient reply, extra insertion could be given. To recrudescent persons, the dosing may be repeated or improved irregularly. But for each muscle the extreme dose should be less than 5 U / inj.
The Dilution of BTXA:
The dilution of BTXA with sterile normal saline has to be done carefully on the basis of real desires. Following is a reference table of watering to be mentioned. The vial must be shaking gradualy after adding sterile normal saline to the whole watering. The watering BTXA (Botulinum Toxin Type A for Therapy) has to be used at once or stored in freezer at 2-8 degrees as well to be administrated within 4 hours. The container as well as the syringe used with this medication also the remaining BTXA solution has to be prepared after purification.
NEGATIVE RESULTS:
Temporary ptosis of the eyelid, negative of the minor eyelid, reduced blinking, eyelid close incompletely, weakness of face muscles, etc. can happen to a few patients who used BTXA remedy for blepharospasm also hemi facial spasm. But, all the symptoms will go without any remedy within 3 to eight weeks. Passing and different degree of ptosis of the eyelid, vertical deviation as well infrequently mydriasis, which related to the diffusion of the toxin to the muscles adjacent, may occur to some individuals who take BTXA (Botulinum Toxin Type A for Therapy) treatment for strabismus. The indications will vanish without any remedy within a few weeks.
CONTRAINDICATIONS:
This injection is contraindicated in patients with anaphylactic parts and known sensitivity to this injection.
CAUTIONS:
The insertion way must be taken later to persons who have temperature, severe infectious diseases and prudently to the people with heart, liver, lung illness, active tuberculosis, blood diseases and pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of drugs should not be used during the injecting of BTXA.
BTXA is in minim result or without any effect to the individuals in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus initiated by extremely serious operation, chronic paralysis strabismus, also chronic VI or III cranial nerve paralysis, severe muscle fiber contracture.
1:1000 adrenalines should be set in case of occasional accident.
EXPIRATION:
Three years from the day of lyophilization. The effect is obvious and can be last 6 months.
STORE:
Keep at a temperature of -5 to -20 gr C (23 to -4 gr F). Store unused vial at -5 temperatures.
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